Carrying a three-goal lead, the Blaugrana will look to reach the Champions League semi-finals.
Lionel Messi and Sergio Busquets both start for Barcelona in the second leg of their Champions League quarter-final at Roma.
The Blaugrana won the first leg 4-1 and will look to complete the job at the Stadio Olimpico on Tuesday.
Busquets returned from a broken toe in the first leg at Camp Nou, but re-aggravated the injury and was forced to miss Saturday’s league match against Leganes.
Messi scored a hat-trick against Leganes, and there was speculation the Argentine star could start from the bench at Roma after only recently returning from a hamstring injury.
For Roma, Radja Nainggolan returns after missing the first leg through injury while Cengiz Under is only fit enough for a place on the bench.